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Research proven benefits of omega-3 fatty acids:
The following are extracted from published clinical studies, in-house studies, and/or case studies and are for reference purposes only. This does not imply that the product from Lifestream Group Pte Ltd is claimed to replicate the same results produced in the studies. This information is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions about a medical condition, please consult your physician or other qualified healthcare providers. Any statements or claims made have not been evaluated by the relevant regulatory bodies and are not intended to diagnose, treat, cure, or prevent any disease.
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Support healthy blood lipids
High triglycerides may contribute to hardening and thickening of the artery walls, increasing the risk of cardiovascular conditions, such as heart attack or stroke. Research suggests that omega-3 fatty acids can help reduce blood triglyceride levels, thereby supporting healthy cardiovascular system.
Study 1: In a clinical trial, diabetic individuals were orally administered fish oil supplement equivalent to 35 mg omega-3 per kg body weight for 3 months. Fish oil supplementation results in a significant reduction of plasma triglyceride level (p < 0.05), suggesting the beneficial effects of omega-3 intake on
blood triglyceride levels (Diabetologia 40: 45–52 (1997)).
Study 2: In this clinical trial, hyperlipidemic subjects were orally administered fish oil that contained approximately 17% EPA, 12% DHA daily for 12 weeks. Compared to control, fish oil administration resulted in a significant reduction of triglycerides, total cholesterol and increase of HDL cholesterol, suggesting the beneficial effects of omega-3 supplementation in hyperlipidemic subjects.
Omega-3 fish oil supports healthy blood lipids
Support healthy blood pressure
Hypertension or high blood pressure increases the risk for almost all different cardiovascular diseases, including stroke, coronary heart disease and heart failure. Besides, it is also an important risk factor for chronic kidney disease and dementia. According to studies, omega-3 fatty acids EPA and DHA
found in fatty fish and fish oil supplements effectively reduces blood pressure. In addition, lifestyle changes, such as exercise, reduced salt intake and limiting alcohol also help reduce high blood pressure.
In this clinical study, peritoneal dialysis patients were orally administered either 3g of omega-3 or placebo per day for 8 weeks and their blood pressure was monitored at baseline and at the end of 8 weeks. At the end of the study, the mean systolic blood pressure decreased in the omega-3 group but increased in the placebo group. Besides, mean diastolic blood pressure decreased more in the omega3 group, compared to the placebo group. These findings indicate that omega-3 fatty acids help reduce blood pressure significantly.
Support cardiovascular health
Cardiovascular diseases are the leading cause of death globally. Omega-3 fatty acids is beneficial to cardiovascular health by reducing the risk of formation of fatty deposits in the arteries and inflammation by inducing the expression of adipokines, such as apelin, which helps protect against incidence and progression of cardiovascular diseases.
In this clinical trial, patients with cardiovascular diseases were orally administered 4g of omega-3 fatty acids (720 mg EPA and 480 mg DHA) or placebo for 8 weeks. Compared to placebo, omea-3 intake significantly increased serum apelin levels (p = 0.018), decreased the levels of LDL (bad) cholesterol and serum hs-CRP (inflammatory marker) concentrations (p = 0.007). Compared to baseline, concentrations of VLDL, triglycerides and hs-CRP and significantly reduced in omega-3 fatty acids group (p < 0.05). These findings suggest the beneficial effects of omega-3 fatty acids to cardiovascular
system.
Support brain health
Alzheimer’s disease may begin 20 years or more before the onset of the symptoms, including changes in memory, thinking or behaviour. Hence, preventive approach for Alzheimer’s disease is of the utmost important. Omega-3 fatty acids are extremely important in brain function and development. Ingestion of omega-3 fatty acids help improve cognitive functions, such as memory, learning, as well as blood flow in the brain.
In this clinical trial, cognitively healthy elderly older adults aged 50 to 75 years were orally administered 2.2 g omega-3 fatty acids or placebo daily for 26 weeks. Omega-3 index and memory performance in the object-location memory (OLM)-task were determined before and after intervention. Compared to the placebo group, omega-3 supplementation significantly increased omega-3 index. Moreover, recall of object locations (OLM-task) was significantly better after omega-3 supplementation. These findings suggest the potential application of omega-3 fatty acids in maintaining cognitive functions in older adults (J Alzheimers Dis. 51(3):713-725 (2016)).
Support emotional health
Depression is a common mental disorder affecting approximately 5% of adults globally. This disorder is associated with continuous depressed mood or sadness and having no motivation or interest in activities for long periods of time. Among the three types of omega-3 (ALA, EPA and DHA), EPA appears to be most effective in managing depression.
In this study, 4150 postmenopausal women were divided into 5 groups according to their dietary omega-3 fatty acid intake, which are 0.3, 0.6, 0.9, 1.4 and 2.7 g/day. The group with the highest dietary omega-3 fatty acid intake shows a significantly lower prevalence of depression that the group with the lowest intake. Besides, the dietary omega-3 intake is inversely proportional to depression in a dose-dependent manner. These suggests the beneficial effects of omega-3 in protecting against and mitigating depression.
Support eye health
i) Help relieve dry eyes
Dry eye happens when the eyes do not produce sufficient tears to provide lubrication for the eyes. This condition commonly occurs in certain situations, such as staring at phone or computer screen for too long or in an air-conditioned room. Among the common symptoms of dry eyes are burning sensation in the eyes, eye redness, watery or teary eyes. Omega-3 fatty acids appear to improve the function of meibomian glands, which secrete oil to coat the surface of the eyes, as well as reduce evaporation of water component of tears, thereby easing dry eye symptoms.
In this clinical study, patients aged 45 to 90 years with dry eye symptoms were orally administered omega-3 fatty acids (360 mg EPA and 240 DHA) or placebo (medium-chain triglyceride oil) daily for 30 days and tear break-up time (TBUT), Schirmer's score, and Ocular Surface Disease Index (OSDI) were determined at baseline and at day 30. TBUT is a clinical test used to assess evaporative dry eye disease. Schirmer test assess if the eyes secrete sufficient tears to keep them moist, while OSDI is a questionnaire to assess symptoms relevant to dry eye disease and their effect on vision. Compared to baseline, improvement in TBUT, Schirmer’s scores and OSDI were significantly better in the omega-3 group than in the placebo group. These findings suggest that consumption of omega-3 fatty acids help reduce rate of tear evaporation, increase tear secretion and improve dry eye symptoms.
i) Support healthy eye pressure
Eye pressure, which is also known as intraocular pressure (IOP) is a measurement of the fluid pressure inside the eyes. Normal ocular pressure is considered between 10 to 20 mm Hg. High IOP or ocular hypertension can add stress on the parts inside the eyes, which can damage the optic nerve. The untreated high eye pressure can cause glaucoma and permanent vision loss. Studies show that lowering ocular pressure could help protect against vision loss from glaucoma. Omega-3 fatty acids help decrease ocular pressure, improve ocular blood flow and exhibit optic neuroprotective function, which could be beneficial to those with high risk of glaucoma.
In this study, adults with IOP <21 mm Hg and without a current or prior glaucoma diagnosis were orally administered omega-3 (~1000 mg/day EPA + ~500 mg/day DHA) or placebo (olive oil, 1500mg/day) daily for 90 days and their IOP was quantified at baseline and after 90 days. Compared to baseline, the IOP was reduce in the omag-3 group and placebo showed a slight increase in IOP at day 90. These findings suggest that omega-3 supplementation for 3 months helps lower IOP in
normotensive subjects.
How to Choose the Best Fish Oil in Singapore
Because our body cannot produce omega-3 on its own, many turn to fish oil to supplement to solve this deficiency. This also means that we should be looking out for the omega-3 mass in the fish oil.
Omega-3 has powerful benefits for the body and the brain. From protecting the heart and easing inflammation to improving mental health.
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Omega-3 fish oil supplements may look similar on the outside, but the potency and benefits can vary drastically! It depends on the fish source, extraction technology and omega-3 mass in the fish oil.
The efficacy of a fish oil correlates with the omega-3 concentration. A research shows that more omega-3 (EPA and DHA) can be detected in the body when a more concentrated fish oil is consumed as compared to multiple lower concentrated fish oils.
Even the best fish oil which has a high dosage fish oil can have blood thinning effect, it is advisable for persons taking blood thinners, such as aspirin to get a medical advice prior to taking omega-3 fish oil supplements.
1. JAMA Netw Open. 1(5): e182327 (2018)
2. British Journal of Clinical Pharmacology. 75(3): 645–662 (2013)
3. Am J Clin Nutr. 96(4): 748–758 (2012)
4. Pharmacol Ther. 141(3):272-282 (2014)
Why The Best Fish Oils Use Omega-3 in rTG Fom
OmaxPure® offers omega-3 in a super absorbable re-esterified triglyceride (rTG) form. Much more bioavailable than the other more common and cheaper alternatives– TG and EE forms, fish oil in rTG form is better tolerated with less gastrointestinal side effects and can be absorbed and utilised more easily by the body. That also means that OmaxPure® can deliver higher doses of omega-3 in smaller amounts of fish oil, thereby allowing each capsule to be highly concentrated, holding up to 90% of omega-3.
Employing Supercritical CO2 Extraction from a 3-layer purification process, this highly advanced purification and concentration technology does not use high heat or toxic solvents, making it more superior to molecular distillation. Maintaining the freshness of fish oil with this oxygen-free manufacturing process,the best fish oil extract is pure and odourless. Heavy metals, cholesterol, other toxic contaminants and solvent residues are removed.
(Modified from “Concentrating omega-3 oils – Supercritical fluid technology versus molecular distillation. Peter Lembke. Published 2011)
For environmental sustainability reasons and to ensure maximum freshness, OmaxPure® only uses small fish sources. Also lower in the food chain, it is less contaminated than bigger fish sources.
To maintain maximum freshness, the fish will be processed in GMP-certified manufacturing facilities located close to or at the harbour.
OmaxPure® is extremely fresh and does not oxidise easily. The absence of reflux or fishy burps is its marker of freshness; unlike other fish oil supplements which would already be oxidised and need an enteric coating to mask the fishy taste of the oxidised fish oil. Rancid fish oil is linked to several detrimental health effects such as an increase of bad cholesterol levels, premature ageing, inflammation, plaque build-up in the arteries, increased free radical generation in the body and even organ damage.
1. Sci Rep. 2015 Jan 21;5:7928.
2. Cardiovasc J Afr. 2013 Sep;24(8):297-302.
3. Laupsa-Borge, Johnny. Velg Ferske og Naturlige Omega-3 Produkter. Helsemagasinet Vitenskap & Fornuft. 9 Dec. 2012.
As seen from the diagram, capsules encapsulated with OmaxFresh® technology releases the contents within 20 minutes. There is little difference between the duration it takes to release from the 1st month and the 4th month. Further enhancing and reinforcing its freshness capability, OmaxPure® is fortified with antioxidants help combat oxidation and rancidity, as well as provide additional health benefits.
• Powerful antioxidant, help minimise free-radical damage to the body
• Gets absorbed and utilised 2 times more efficiently than the synthetic form
• Complements and enhances the benefits of fish oil - anti-inflammation, improved skin health and brain function
• Strong antioxidant capacity, synergistic antioxidant effect with natural vitamin E
• Helps delay the onset of oxidation
• Neutralise free radicals
• Help boost immune system
• Improve blood circulation
• Improve digestion
• Protect against brain ageing
• Promote eye health
You would only need 1 softgel of the best fish oil to fulfil the recommended omega-3 dosage. But if other fish oils contain less omega-3 content, how many fish oil softgels will it take to meet the recommended dosage?
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The expiry date and smell of the fish oil can give some indication of the freshness of the fish oil. But for a good measure of the quality and freshness, a responsible fish oil manufacturer will commission an independent testing organisation who does not benefit financially from the test results to test their products. It is important to ensure that even the best fish oil abides by international standards set by third party omega-3 trade bodies such as GOED.
Independent third party organisationsexist to set recommendedinternational standards and criteria for fish oil manufacturersto comply by.Such organisations include:
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