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URICRestore

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URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
New -22 %
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore
URICRestore

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S$42.90
S$54.90
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Ex GST: S$39.36
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Active ingredients per 1 veggie capsule: 


Vitamin C(as ascorbic acid) 100mg

Proprietary Blend: 289mg
• SunActive IsoQ (Cyclodextrin, isoquercitrin, rhamnose)
• LuteoPure Luteolin 98% (Standardised Extract 98%)

BioPerine Black Pepper Extract 5mg

Other Ingredients: Starch, Silicon Dioxide, Calcium Stearate, Hydroxypropyl methylcellulose (HPMC)

CONTAINS: PEANUT

No Gluten, Wheat, Milk Derivatives, Preservatives, Artificial Flavoring

 


 

1 capsule daily 
 

Q: What makes URICRestore unique and how does it work?
A: URICRestore is a comprehensive formula made with two powerful flavonoids that work synergistically to support healthy uric acid levels and overall wellness. SunActive® IsoQ (isoquercitrin) is a quercetin precursor produced using proprietary microencapsulation technology with 25X more bioavailability than quercetin and 4X better absorption than other isoquercitrin. It teams up with LuteoPureTM Luteolin 98% (Luteolin extract with 98% standardization) to help balance and cleanse uric acid and relieve joint discomforts. This formula is proven to help relieve gout-induced joint discomfort by up to 18% in 2 days.
URICRestore is also vegan-friendly and packed with antioxidants that help support healthy inflammatory response, maintaining healthy joints, kidneys and liver, organs that can be affected by high uric acid. Beyond uric acid, it offers potential benefits for immune health, heart health, and respiratory health as well. Additionally, the formula includes Vitamin C and BioPerine® black pepper extract to enhance the efficacy of this formula.

 

Q: How does URICRestore manage high uric acid levels?
A: URICRestore tackles high uric acid levels through a multi-pronged approach. Firstly, it helps suppress specific enzymes involved in uric acid production within the body. Secondly, URICRestore addresses the impact of high fructose intake on uric acid metabolism. Excessive fructose consumption can lead to both increased production and decreased excretion of uric acid, raising the risk of gout. This formula works to regulate this process. Finally, URICRestore promotes healthy uric acid excretion by the kidneys. It does this by influencing transporters – increasing the activity of those that expel uric acid and suppressing those responsible for reabsorption. This combined action helps alleviate hyperuricemia (high uric acid in the blood) and potentially improves kidney function.

 

Q: What are the health benefits expected from URICRestore?
A: URICRestore offers a comprehensive approach to managing high uric acid and promoting overall well-being:
Manages Uric Acid Levels: The synergistic combination of SunActive® IsoQ and LuteoPureTM Luteolin helps maintain healthy uric acid levels, potentially reducing the risk and frequency of gout attacks. Studies have shown this formula can reduce gout-related joint discomfort by up to 18% in 2 days.
Promotes Joint Health: As a vegan formula packed with antioxidants, URICRestore supports a healthy inflammatory response and helps maintain healthy joints, all of which can be impacted by high uric acid levels.
Supports Organ Health: URICRestore protects organs like the kidneys and liver, which are susceptible to damage from high uric acid.
Enhances Overall Wellness: These powerful flavonoids go beyond uric acid management. They also promote immune health, cardiovascular health, and overall well-being.

 

Q: How to take URICRestore for optimal results?
A: The recommended dosage for URICRestore is 1 capsule daily. For the best results, it's recommended to take it after dinner or before bedtime. Gout attacks often occur at night, potentially due to lower body temperature and increased dehydration during sleep. These conditions can contribute to uric acid buildup. Taking URICRestore after dinner or before bedtime may offer greater protection against gout flare-ups by potentially supporting healthy uric acid levels throughout the night.

 

Q: Should I increase the dosage of URICRestore during gout flare-ups?
A: Yes, it is safe to temporarily increase the dosage of URICRestore to up to 4 capsules daily during gout flare-ups. It is best to take the 4 capsules separately throughout the day for sustained benefits. For additional support during a gout flare-up, you may want to complement with FlexC MAX EX to expedite the discomfort relief. FlexC MAX EX is a powerful formula targeting inflammation for effective pain relief.

 

Q: How fast can I see the results?
A:
Studies suggest URICRestore could result in a significant reduction of blood uric acid levels within just 2 weeks of intake. Additionally, the powerful anti-inflammatory properties of URICRestore may contribute to some relief from gout-induced discomfort by up to 18% as early as 2 days after intake. Beyond gout, this vegan formula extends its potential benefits to those managing rheumatoid arthritis. Taking URICRestore for 8 weeks could significantly reduce morning stiffness and pain associated with rheumatoid arthritis, both upon waking and after activity.

 

Q: Should I continue taking URICRestore when my uric acid levels have restored to healthy levels?
A:
Yes, even after achieving healthy uric acid levels, continuing URICRestore can help maintain this healthy balance. The body naturally produces uric acid, and certain foods are high in purines and fructose, which can also contribute to high uric acid and gout. Hence, continuing URICRestore long-term can help maintain optimal uric acid level and reduce the risk of gout recurrence and other complications associated with high uric acid.

 

Q: Are there any side effects associated with consumption of URICRestore? 
A:
URICRestore is generally a well-tolerated supplement with no known side effects. It is safe for long-term consumption for maintaining healthy uric acid levels and reducing the risk of recurring gout attacks.  However, please get medical advice before starting any health supplements if you are pregnant, lactating, have any health conditions and / or taking any medications.

 

Q: Who can benefit from URICRestore?
A:
URICRestore is formulated to support healthy uric acid levels and may be beneficial for several groups of people:
Individuals with high uric acid levels
Those experiencing gout symptoms such as joint pain, swelling, and redness
Seafood (high-purine) lover and alcohol lover 
High fructose intake
Additionally, URICRestore's vegan formula makes it suitable for those with dietary restrictions.

 

Q: Is URICRestore suitable for vegetarians?
A:
Yes, URICRrestore is 100% vegan-friendly and suitable for vegetarians and vegans alike. Its key components, LuteoPureTM Luteolin 98% extracted from peanut shells and SunActive® IsoQ derived from rutin (a plant pigment found in Japanese Pagoda tree flower buds), are plant-based.

 

Q: Does URICRestore require a prescription?
A:
No, URICRestore is a natural dietary supplement. It is not a medicine and hence, no prescription is required. However, it's always a good practice to consult with your doctor before starting any new supplement, especially if you are pregnant, lactating or have any pre-existing health conditions or are taking medications.

 

Q: Can I take URICRestore while I am on medication?
A:
Yes, you can. Please keep at least a 2-hour gap between URICRestore and medicines to obtain the full effects of this supplement.

 

Q: Can I take URICRestore along with other supplements?
A:
It's generally safe to take URICRestore with other supplements, but it's always recommended to consult with a healthcare professional before starting any new supplements.

 

Q: Can children take URICRestore?
A:
URICRestore is formulated for adults. However, children aged 4 and above can take 1 capsule of UricRestore daily to harness the health benefits of Luteolin and Isoquercitrin (precursor of quercetin). They are two powerful flavonoids with antioxidant and anti-inflammatory properties, which are crucial for optimal immune system, brain health and overall body wellness. 

 

Q: Since peanuts contain purines, should I be concerned about taking URICRestore because the luteolin is extracted from peanut shells?
A:
You raise a good point! Peanuts do contain a moderate amount of purine. However, the luteolin in URICRestore is extracted from PEANUT SHELLS using a proprietary technology which make it free from purine. However,  If this is still a concern,  we suggest consulting with a doctor before taking URICRestore

 

Q: What are the symptoms of high uric acid?
A:
Not everyone with high uric acid will experience symptoms. This is why a blood test is often used to diagnose it. However, some symptoms of high uric acid can include:
Gout: This is the most common symptom which is characterized by sudden and intense pain, swelling, redness, and tenderness in the joints, often at the base of the big toe.
Kidney stones: High uric acid levels can contribute to the formation of kidney stones, which can cause severe pain in the lower back, side, or abdomen, along with pain or burning during urination.

 

Q: Who is susceptible to high uric acid?    
A:
High uric acid can affect anyone, but it's more common in men than women. This is because female hormone estrogen helps flush out uric acid. However, after menopause, estrogen levels decline, which can contribute to higher uric acid levels in women.
There are several risk factors associated with high uric acid and gout, which include alcohol consumption, purine- and fructose-rich foods, dehydration, obesity, kidney disease, high blood pressure and high blood glucose. 

The following are extracted from published clinical studies, in-house studies, and/or case studies and are for reference purposes only. This does not imply that the product from Lifestream Group Pte Ltd is claimed to replicate the same results produced in the studies. This information is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions about a medical condition, please consult your physician or other qualified healthcare providers. Any statements or claims made have not been evaluated by the relevant regulatory bodies and are not intended to diagnose, treat, cure, or prevent any disease.

By using the Site, you agree that you have read and acknowledge the above and the Terms of Use for this Site.

Research Proven Health Benefits:

Support healthy blood uric acid levels

Hyperuricemia is a major risk factor for gout, which results in a very painful joint pain. Besides, the elevated blood uric acid levels are also associated with the development of life-threatening conditions, including chronic kidney disease and cardiovascular disease. Hence, managing high uric acid levels is of utmost important for optimal health.


Study 1:
In this clinical trial, healthy male volunteers with high plasma uric acid, but still considered healthy range (339 ± 51 μmol/L) were administered 500 mg quercetin or placebo daily for 4 weeks and plasma uric acid levels were compared at baseline, 2 and 4 weeks after consumption. Compared to placebo, quercetin group showed significant reduction of plasma uric acid levels by 26.5 μmol/L, which is equivalent to around 8% reduction, without affecting urinary excretion of uric acid, BMI, fasting glucose or blood pressure. These finding suggests the beneficial effects of quercetin in reducing elevated blood uric acid levels in pre-hyperuricaemia individuals.

Study 2:
In this clinical trial, patients with gout and essential hypertension (abnormally high blood pressure that is not the result of a medical condition) were orally
administered quercetin or control (without quercetin) in addition to antihypertensive and uric acid-lowering regimens for 12 months. Compared to control, quercetin showed lower blood uric acid levels and the patients in the quercetin group achieved the target uric acid level (reduction by 33.7%) faster than the patients in the control group. In addition, patients in the quercetin group showed better heart health and kidney function, as well as lower blood pressure, compared to control. These findings suggest the potential benefit of adding quercetin to antihypertensive and uric acid-lowering regimens in normalising uric acid, kidney function and blood pressure (Wiad Lek. 71: 1554–1559 (2018)).

 

Study 3:
In this clinical trial, fasting Japanese men with mild hyperuricemia were administered 100 mg luteolin-rich chrysanthemum flower extract (LCE), which contained 10 mg of luteolin or placebo before taking a meal that is high in purine for 4 weeks and their fasting blood uric acid levels were determined. After 4-week of LCE administration, a significant reduction of blood uric acid levels in the subjects with baseline uric acid of 5.5 to 7.0 mg/dL, without adverse effects observed during or after ingestion of LCE. These findings suggest the potential application of luteolin in protecting against gout by controlling uric acid levels.

Helps relieve joint discomfort

A) Gout
Gout is a common type of inflammatory arthritis that causes sudden and painful joints, particularly in the big toe. This condition is caused by excess uric acid in the blood, which form crystals that build up in the joints. Gout can cause joint damage if left untreated.
In this animal test, rats were induced gouty arthritis by intra-articular injection of monosodium urate (MSU) crystal suspension inside the ankle joint of the rat right hind limb. Administration 400 mg/kg quercetin suppressed joint
edema and histological signs of acute inflammation. Besides, quercetin administration resulted in decreased levels of inflammatory mediators, including interleukin–1β (IL-1β), tumour necrosis factor–α (TNF-α), as well as increased antioxidant enzyme activity of superoxide dismutase (SOD) and catalase (CAT). These findings suggest the strong anti-inflammatory effect of quercetin and its potential application for mitigating gouty arthritis

 

B) Rheumatoid arthritis

Rheumatoid arthritis is an autoimmune and inflammatory disorder, leading to painful and swollen joints. This happens when the immune system does not work properly and attack the lining of the joints by mistake. In this clinical trial, women with rheumatoid arthritis were orally administered 500 mg/day quercetin or placebo for 8 weeks. Quercetin administration for 8 weeks significantly reduced early morning stiffness (EMS) and morning and after-activity pain. Compared to placebo, quercetin group showed decreased DAS-28 score, which is a measure widely used to determine disease activity in rheumatoid arthritis, with a higher number indicating more active disease. Besides, the plasma levels of hs-TNFα (high-sensitivity tumor necrosis factor-α), an inflammatory cytokine, was significantly reduced in quercetin group, compared to placebo. These findings suggest the beneficial effects of quercetin supplementation in improving clinical symptoms and disease activity in those with rheumatoid arthritis. (J Am Coll Nutr. 36(1): 9-15 (2017)).

 

Support liver health

High uric acid levels have been associated with liver dysfunction through different mechanisms. Elevated uric acid can induce inflammation and oxidative stress, leading to liver cell death and impaired liver function.

In this study, Monosodium urate (MSU) crystals was used to induce liver inflammation and Acetaminophen (AMP) was used to induce liver injury in rats and the rats were administered 30 mg/kg or 50 mg/kg luteolin and compared to colchicine, a medicine that is used to prevent and treat gout attacks. To evaluate the effects of luteolin, uric acid level, neutrophil infiltration, rat paw edema, lysosomal enzymes, antioxidant status and cytokine level were measured. Compared to control group in MSU crystal-induced rat, luteolin significantly decreased paw edema in a dose-dependent manner. In addition, administration of luteolin at 50 mg/kg showed significant reduction in serum level of oxidative and lysosomal enzymes, proinflammatory cytokines (TNF-α, IL-1β and IL-6) in MSU crystal-induced rats. In AMP-induced liver injury, tissue uric acid level and serum levels of liver enzymes decreased significantly after treatment with luteolin. These findings support that the anti-inflammatory activity of luteolin through restoration of cytokine level, lysosomal enzymes level and antioxidant status. The reduction of liver tissue uric acid content may be one of the protective mechanisms of luteolin, which can reduce injury induced inflammation in the liver.

 

 

Support kidney health

High blood uric acid levels and gout may harm the kidneys. As the kidneys filter the blood, uric acid can build up and form crystals, which can cause damage and scars to the kidneys. This kidney damage would likely lead to kidney disease and failure, if high uric acid or gout is left untreated. 

Study 1:

In this animal test, mice with oxonate-induced hyperuricemia were orally administered water (control), 25, 50 or 100 mg/kg quercetin respectively for 1 week and blood uric acid level and excretion of uric acid were analysed after 1 week of administration. Compared to control, quercetin significantly restored oxonate-induced abnormalities of the biochemical indexes. In addition, quercetin remarkably suppressed the expression changes of renal organic ion transporters and uromodulin (UMOD), which are crucial for uric acid excretion by the kidneys, as well as kidney function. These findings suggest the beneficial effects of quercetin in excreting uric acid and maintaining health kidney function (European Journal of Nutrition 51: 593-606 (2012)).

Uric acid crystals are suggested to promote the formation and growth of calcium oxalate crystals, which are the most common cause of kidney stones. Besides, there is an association between oxidative stress and kidney stone pathogenesis. Quercetin, which has strong antioxidant and anti-inflammatory properties, could potentially help manage kidney tissue injury in kidney stone disease.


Study 2:

In this study, the ability quercetin at various concentrations (2.5, 5, 10, 20, 40, 80 and 160 μM) to modulate calcium oxalate crystallisation was investigated. Results showed that quercetin significantly suppressed calcium oxalate crystallisation and crystal growth in a concentration-dependent manner. These findings suggest the potential use of quercetin in reducing the risk of developing kidney stones. 

Supports healthy blood glucose

High uric acid could cause injury to pancreatic beta-cells, which secrete insulin that lowers the blood glucose concentration. The impairment of uric acid secretion could result in chronic hyperglycermia, which characterises type 2 diabetes. Besides, high uric acid increases production of reactive oxygen species, which can induce oxidative stress and contribute to abnormal glucose metabolism. 


In this study, the effects of luteolin on uric-acid induced inhibition of glucose-stimulated insulin secretion (GSIS) in Min6 cells (mouse pancreatic beta cell line) and freshly isolated mouse pancreatic islets were investigated. Results showed that luteolin prevented uric acid-induced inhibition of GSIS in both Min6 cells and mouse islets. This suggests that luteolin helps protect pancreatic beta cells from uric-acid induced dysfunction and may be beneficial to hyperuricemia-associated diabetes. 

Support healthy blood pressure

Elevated uric acid is a strong risk marker for developing hypertension from prehypertension. Uric acid plays a crucial role in the development of high blood pressure, which could be due to oxidative stress, systemic inflammation and endothelial dysfunction. 

In this clinical trial, stage 1 hypertension individuals were orally administered 730 mg quercetin or placebo daily for 28 days. Results showed that systolic, diastolic and mean arterial pressures reduced in the patients after quercetin administration, suggesting the beneficial effects of quercetin on cardiovascular health.


Support healthy blood lipids

There is a positive correlation exists between blood uric acid and cholesterol levels. Blood uric acid has been suggested to be a strong predictor of stroke, coronary artery disease and metabolic syndrome. 


In this study, the effect of luteolin and quercetin on cholesterol absorption was evaluated using Caco-2 cells (colon epithelial cells) and rats. When Caco-2 cells were preincubated with luteolin and quercetin, cholesterol uptake by the cells were significantly decreased and these inhibitory effects were maintained for up to 120 minutes. Compared to cholesterol feeding group, rats fed both cholesterol and luteolin or quercetin showed significantly greater reduction of blood cholesterol levels. These findings suggest luteolin and quercetin could potentially help reduce high cholesterol levels by suppressing intestinal cholesterol absorption. 


 

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