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Liposomal Vitamin D3

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Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
New -26 %
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3
Liposomal Vitamin D3

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S$28.90
S$38.89
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Ex GST: S$26.51
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Per 1 veggie softgel

Vitamin D3(as Cholecalciferol) 25mcg(1,000 IU)

Other ingredients: Coconut MCT Oil, Sunflower Lecithin, Gum Arabic, Glycerin Fatty Acid Ester, Gelatin-free Capsule (Modified Starch, Glycerol, Carrageenan from Seaweed)

1 veggie softgel daily

Q: What is Liposomal Vitamin D3 supplement?
A:
Different from regular vitamin D3, Liposomal Vitamin D3 encapsulates vitamin D3 in liposomes. This liposomal encapsulation enhances the absorption and bioavailability of vitamin D3, a fat-soluble vitamin. Liposomes have a similar structure to our cell membrane By fusing with cell membranes, liposomes deliver vitamin D3 directly into cells, maximizing its delivery to target organs and tissues. Compared to oily formulations of vitamin D3, liposomal encapsulation technology offers up to 470% greater bioavailability. Moreover, liposomes protect vitamin D3 from degradation and oxidation as it
moves through the body, while also shielding it from the harsh conditions of the digestive tract and further enhancing its efficacy. Liposomal Vitamin D3 is also a vegan-friendly supplement. While most vitamin D3 sourced from sheep’s wool (lanolin), Liposomal Vitamin D3 is sourced from lichen, which is a leaf-like structure generally develops on the trees. This is one of the first completely vegan sources of natural vitamin D3 available on the market and it is chemically identical to animal sources of vitamin D3. Unlike vitamin D3 made from lanolin, Liposomal Vitamin D3 has no risk of contamination by sheep dip or pesticides. Additionally, lichen can be cultivated extensively, ensuring a more sustainable
approach to vitamin D3 production.

 

Q: How is Liposomal Vitamin D3 superior as compared to other vitamin D3 supplements?
A:
Liposomal Vitamin D3 stands out from regular vitamin D3 supplements due to its liposomal encapsulation and lichen-derived vitamin D3, offering quicker and more effective results.

•Vegan-friendly: Unlike conventional vitamin D3 often sourced from sheep's wool, Liposomal Vitamin D3 utilizes lichen, a plant-based source, making it suitable for all, including vegans.
•Non-GMO and gluten-free 
•Enhanced absorption and bioavailability: The liposomal encapsulation technology enhances the absorption and bioavailability of vitamin D3 by up to 470% compared to oily formulations.
•Direct cellular delivery: Liposomes fuse with cell membranes, delivering vitamin D3 directly into cells, maximizing its utilization by the body.
•Sustained release: Liposomal Vitamin D3 provides a sustained release of vitamin D3 into the bloodstream, for continued benefits
•Protection from degradation: Liposomes protect vitamin D3 from degradation and oxidation, ensuring its stability and effectiveness.
•Gentle on the digestive system: Liposomal Vitamin D3 is less likely to cause gastrointestinal discomforts often associated with regular vitamin D3 supplements.

 

Q: How does liposomes help improve absorption and bioavailability of vitamin D3?
A:
Liposomes are microscopic, spherical-shaped vesicle that forms membrane made of phospholipid bilayers, which closely resembles the structure of cell membranes. This structural similarity enables liposomes to fuse with the cells in the intestinal lining more readily, facilitating the transfer of vitamin D3 directly into the bloodstream. This enhanced absorption means that more vitamin D3 would become available for use by the body, increasing its efficacy. These liposomes also serve as a protective barrier around vitamin D3, which helps vitamin D3 survive the harsh conditions of the digestive system, allowing it to be absorbed intact in the small intestine.

 

Q: What is the best time to consume Liposomal Vitamin D3 supplement?
A:
It is advisable to take Liposomal Vitamin D3 with a meal that contains some healthy fats. Vitamin D is fat-soluble and absorption can be further enhanced by the presence of dietary fats, together with liposomal encapsulation technology. Avoid taking vitamin D3 together with caffeinated beverages, such as coffee and tea, as caffeine can hinder vitamin D3 absorption.

 

Q: What are the symptoms of vitamin D deficiency?
A:
Most people with vitamin D deficiency are asymptomatic. However, these could be some potential signs of vitamin D deficiency.
•Bones and muscle weakness: A deficiency can lead to weak bones and muscles, chronic back pain, particularly in the legs, ribs or joints
•Mood swings: It may also extend to poor sleep, fatigue or even depression.
•Weakened immunity: Vitamin D is essential for strong immune system. Low vitamin D could lead to poor immunity and cold. Other signs include a loss of appetite, pale skin and severe hair loss, especially in women and slow healing of wounds.

 

Q: What are the benefits in taking Liposomal Vitamin D3?
A:
Liposomal Vitamin D3 helps increase and maintain vitamin D levels in the body, which is crucial for overall body wellness. Vitamin D promotes absorption of calcium and phosphate, allowing bone and tooth mineralisation, which keep them strong and healthy. Besides, vitamin D supports muscle function, which could help reduce the risk of muscle weakness and falls. In addition to bone and muscles, adequate vitamin D also supports healthy immune system and helps promote a mood. Besides, vitamin D helps regulate blood glucose levels and blood pressure, improve heart function and reduce the risk of major cardiovascular events, such as heart attacks. Other than these, maintaining healthy levels of vitamin D is essential for overall wellness, including cell growth, healthy inflammatory response, hormonal balance, energy boost and healthy weight management.

 

Q: Who should consume Liposomal Vitamin D3 supplement?
A:
Although vitamin D can be produced naturally in the skin when exposed to sunlight, vitamin D
deficiency is a major concern worldwide for all age groups. The major causes of vitamin D deficiency are insufficient exposure to sunlight, very few foods naturally contain sufficient vitamin D and those fortified with vitamin D are usually insufficient to meet the daily required dosage. Hence, no one is immune from vitamin D deficiency. Liposomal Vitamin D3 is essentially for everyone, particularly those who have limited exposure to sunlight, such as individuals working indoors. Besides, older adults, people with darker skin tones and those with medical conditions affecting vitamin D absorption may also benefit from the supplementation. Individuals with limited sunlight exposure, strict vegans or vegetarians should also consider Liposomal Vitamin D3 to increase and maintain healthy vitamin D levels.

 

Q: Can I give Liposomal Vitamin D3 to my child?
A:
Yes, you can. Many children do not get sufficient vitamin D through their diet and deficiency of vitamin D is common among children. The daily vitamin D requirement for children is 400 to 600 IU, but the optimum daily dosage is 1000 IU (J Clin Endocrinol Metab. 2011 Jul;96(7):1911-1930), which is equivalent to 1 softgel of Liposomal Vitamin D3. If swallowing the whole softgel is not possible, the vitamin D can be squeezed into milk or food for ease of consumption.

 

Q: From what age should we start taking vitamin D?
A:
All children require vitamin D beginning shortly after birth and continuously meeting the daily required dose of vitamin D is important for children. Prolonged and extreme vitamin D deficiency can cause rickets, which is a condition affects bone development, causing softening and weakening of bones in children, leading to bone deformities. Babies younger than 12 months old require 400 IU of vitamin D daily, while toddlers, older children and adolescents require 600 IU of vitamin D daily (The Academy of Pediatrics (AAP)). Although the daily vitamin D requirement for children is 400 to 600 IU, but a study suggested 1000 IU as the optimum daily dosage (J Clin Endocrinol Metab. 2011 Jul;96(7):1911-1930), which is equivalent to 1 softgel of Liposomal Vitamin D3.

 

Q: Can I take more than recommended vitamin D3, which is 1000 IU?
A:
Yes, you can. Vitamin D deficiency is a common concern for all age groups, with about 1 billion people worldwide have vitamin D deficiency and 50% of the population has vitamin D insufficiency. The precise amount of vitamin D required by the body depends on many factors. Older adults (over the age of 65 years old), those with darker skin tone, or are living in high latitude, or experience winter seasons with limited sun exposure, or people living with obesity may need a higher amount of vitamin D. Toxicity is unlikely if the daily intake levels are kept below 10,000 IU per day.

 

Q: How long should I take Liposomal Vitamin D3 for?
A:
Taking Liposomal Vitamin D3 consistently for long-term is the best way to maintain optimal health. Similar to majority of supplements, vitamin D supplementation does not work overnight. Research shows that the greatest rise in vitamin D levels came between 3 to 9 months after beginning supplementation. Vitamin D levels, measured as serum 25(OH)D, are expected to rise by about 1ng/mL for every daily 100 IU (2.5 mcg) vitamin D supplementation (Clin J Am Soc Nephrol. 2008 Sep;3(5): 1535–1541). The normal range of 25(OH)D is recommended to be between 20 and 40 ng/mL. The dosage needed to increase serum 25(OH)D levels is generally higher and the dosage needed varies from person to person. Dosages of vitamin D between 3000 to 5000 IU (75 to 125 mcg) are recommended to maintain healthy serum levels in healthy men.

 

Q: Is Liposomal Vitamin D3 supplement safe for use during pregnancy and nursing?
A:
Liposomal Vitamin D3 supplement has not been studied for use during pregnancy and nursing. If you are pregnant or nursing, we strongly advise you to consult your physician before taking any supplements.

 

Q. Does Liposomal Vitamin D3 supplement require a prescription?
A.
No, Liposomal Vitamin D3 is not a medicine. It is a natural supplement; hence, no prescription is required.

 

Q. Can I take Liposomal Vitamin D3 supplement while I am on medication?
A.
Yes, you can. However, do keep a 2-hour gap between Liposomal Vitamin D3 and medicine to ensure that the efficacy of Liposomal Vitamin D3 is not compromised.

 

Q: How does vitamin D3 differ from vitamin D2?
A:
Vitamin D2 and D3 are the two main forms of vitamin D. While both of them help correct vitamin D deficiency, vitamin D3 is more effective in increasing vitamin D levels in the bloodstream for a longer period than vitamin D2. A study comparing vitamin D2 and D3 concluded that vitamin D3 is approximately 87% more potent in increasing and maintaining serum 25-hydroxyvitamin D (25(OH)D), which is the major circulating form of vitamin D in the blood. Besides, vitamin D3 produces 2 to 3-folder higher storage of vitamin D compared to vitamin D2 (Clinical Journal of Endocrinology Metabolism (2011)). Hence, the choice between these forms depends on dietary preferences and individual needs, with healthcare professionals often recommending vitamin D3 due to its potential effectiveness in raising and maintaining vitamin D levels. Liposomal Vitamin D3 is however different from most vitamin D3. Unlike most vitamin D3 which derived from animals, the vitamin D3 in this formula is sourced from lichen and hence, it is suitable for vegans and vegetarians. With liposome encapsulation technology, the efficacy of vitamin D3 is more superior than regular vitamin D3, delivering quicker and more effective results.

Research Proven Health Benefits:

The following are extracted from published clinical studies, in-house studies, and/or case studies and are for reference purposes only. This does not imply that the product from Lifestream Group Pte Ltd is claimed to replicate the same results produced in the studies. This information is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions about a medical condition, please consult your physician or other qualified healthcare providers. Any statements or claims made have not been evaluated by the relevant regulatory bodies and are not intended to diagnose, treat, cure, or prevent any disease.

By using the Site, you agree that you have read and acknowledge the above and the Terms of Use for this Site.

 

Greater absorption with Liposomal Vitamin D

Liposomes are a vesicular-form drug delivery system composed of phospholipid bilayer. Liposomes are used to encapsulate nutrients, protecting them against harsh gastric acid in the stomach, while enhancing their absorption and bioavailability. High
bioavailability is important for nutrients to reach their maximal efficacy and health outcomes.

In this clinical study, healthy volunteers aged 24 to 65 years old were orally administered 10,000 IU vitamin D3 either in the liposomal or oily formulation for 3 weeks and vitamin D3 absorption was evaluated by quantifying concentration of 25(OH)D3, which is the major circulating form of vitamin D3 in the blood before and 0.5, 1, 1.5, 2, 3, 4 and 5 hours following the intake of vitamin D3.


To determine the increase of 25(OH)D3 after supplementation, initial quantity of 25(OH)D3 was subtracted from its values for samples collected at later time points and normalized to the initial value [(A(t) − A0)/A0]. The tendency of 25(OH)D3 change was approximated with the linear function using the least square fitting. The average values of slopes were equal to 7.03 × 10−5 1/min ± 3.02 × 10−4 1/min and 4.01 × 10−4 1/min ± 7.12 × 10−4 1/min for oily and liposome formulations, respectively.
This shows that the liposome formulation delivers vitamin D3 within hours of supplement, whole oily formulation does not produce any effect within the same time intervals. This effect is particularly prominent for those with severe vitamin D3 deficiency. These findings suggest that liposomal encapsulation technology helps enhance bioavailability of vitamin D3.

Increase calcium absorption

Optimal vitamin D levels are essential to promote calcium absorption in the gut and maintain sufficient calcium and phosphate concentration, supporting normal bone mineralisation and healthy bones.

In this clinical study, 12 previously untreated patients with postmenopausal osteoporosis were orally administered 0.5 μg/day 1,25-dihydroxyvitamin D3 (active vitamin D metabolite) for 6 to 8 months and their effect on bone and calcium metabolism were determined. Administration of 1,25-dihydroxyvitamin D3 improved calcium absorption, calcium balance and bone formation rate exceeded bone resorption rate. Bone loss would occur if bone resorption rate is greater than bone formation rate. These findings suggest that 1,25- dihydroxyvitamin D3 helps normalise calcium absorption, calcium balance, and support bone health.

Support muscle health

Vitamin D plays a vital role for optimal functioning of muscles. Vitamin D supplementation has been shown to increase muscle strength, especially for those with vitamin D deficiency.

In this clinical trial, 60 male volunteers aged 20 to 24 years old with suboptimal plasma vitamin D (25(OH)D) plasma levels were given vitamin D supplementation for 3 months. These participants were subjected to 2 rounds of eccentric exercise tests (muscle contractions that lengthen a muscle) on a declined treadmill before the supplementation (Test I) and after 3 months of administration (Test II). After a 3-month vitamin D supplementation, higher concentrations of blood vitamin D(25(OH)D) were detected compared to baseline. Besides, there was a significant decrease (p = 0.047) in Interleukin- 1β(IL-1β) (a potent pro-inflammatory cytokine) levels 1 hour before exercise in Test II, compared to Test I. In addition, lower myoglobin (Mb) concentrations were observed 1 hour after exercise. Higher Mb concentration may indicate damaged muscle tissues. These findings suggest that vitamin D helps reduce muscle cell damaged induced by eccentric exercise.

Support healthy inflammatory response

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that causes chronic recurrent inflammation of the colon. This condition may be related to vitamin D deficiency and vitamin supplementation may help ameliorate the intestinal inflammation.

In this clinical trial, 90 mild-to-moderate UC patients were administered a single muscular injection of 7.5 mg vitamin D3 or 1 mL normal saline as placebo. Their serum levels of inflammatory-related cytokines IL-12p70, IFN-γ, and TNF-α)were measured 3 months later. Results showed a significant increase in vitamin D only in the vitamin D group. Compared to placebo, vitamin D significantly decreased the serum TNF-α, IFN-γ, and IL12p70 levels, which are inflammatory-related cytokines. These findings suggest the potential of vitamin D in modulating inflammatory response (APMIS. 127(10): 681-687 (2019)).

Support oral health

Severe vitamin D deficiency in children could affect tooth mineralisation, resulting in dentin and enamel defects, which would increase the risk of onset and progression of dental caries.

In this clinical trial, children and adolescents with juvenile idiopathic arthritis (JIA) aged 4 to 16 years with median age of 12.6 years were involved. The mean serum vitamin D level was 61.4 nmol/L and 29.6% of participants had insufficient levels. Vitamin D insufficiency was associated with dental caries and gingival bleeding (bleeding gums). These findings suggest a correlation between vitamin D status and oral health (BMC Oral Health. 22(1): 333 (2022)).

Support cardiovascular health 

Studies have suggested the association between low vitamin D levels in the blood and increased risks of cardiovascular conditions, including heart disease, stroke and hypertension and diabetes. Hence, vitamin D holds the potential in protecting against cardiovascular disease (CVD) and type 2 diabetes.

In this clinical trial, participants aged 60 to 84 years old were orally administered 60,000 IU/month vitamin D3 or placebo for up to 5 years. Results showed that 6.6% participants in placebo group and 6.0% participants in vitamin D group experienced a major cardiovascular event. Compared to placebo group, the rate of major cardiovascular events was lower in the vitamin D group, especially among those taking cardiovascular drugs at baseline. In addition, the rate of myocardial infarction (heart attack) and coronary revascularisation (a procedure to improve blood flow to the heart) was lower in the vitamin D group. These findings suggest the potential of vitamin D supplementation in reducing the incidence of major cardiovascular events.

Support healthy blood pressure

Persistent blood pressure would impose extra strain on the blood vessels, heart, and other organs, increasing the risk of life-threatening health conditions such as heart disease. Some studies associated low vitamin D level with an increased risk of high blood pressure and diabetes.

In this clinical trial, type 2 diabetes patients were administered vitamin D (cholecalciferol) supplementation at 50,000 units weekly or control for 12 weeks and their systolic and diastolic blood pressure (BP) was determined before and after intervention. Before intervention, the means of systolic BP and diastolic BP were 121 and 80.5 mmHg, respectively. After intervention, the systolic and diastolic BP were 110 and 76.3 mmHg, respectively. Compared to control, systolic and diastolic blood pressure levels were significantly lower (p < 0.01) in vitamin D group after intervention. These findings suggest that vitamin D supplementation may help improve high blood pressure in type 2 diabetic patients.

Support mental health

Depression is a common mental disorder that involves a depressed mood, such as feeling sad, irritable and empty, or a loss of pleasure or interest in activities. Many people with depression have low blood levels of vitamin D. Hence, vitamin D
deficiency may be associated with depression.

In this clinical trial, older adults aged over 60 years with moderate to severe depression were orally administered 50,000 IU vitamin D3 weekly or placebo for 8 weeks. Compared to placebo group, there was remarkable increase in 25(OH)D3 concentration in vitamin D group. Besides, the depression score of GDS-15 (Geriatric Depression Scale-15) questionnaire significantly decreased (p = 0.0001) in vitamin D group, while there was a non- significant increase in depression score in placebo group. These findings suggest that vitamin D supplementation could help improve depression score in older adults.

Boost energy levels

Fatigue, which is a feeling of constant tiredness, lack of energy or burnout, can result in slowed reaction time, reduced vigilance and impaired decision making and judgement. Vitamin D deficiency has been associated with fatigue and other unspecified symptoms, such as headache, depression and poor cognitive performance.

In this clinical trial, adults who were fatigue and had low vitamin D levels were administered vitamin D for 5 weeks. The prevalence of vitamin D was 77.2% in adults with fatigue. Fatigue assessment questionnaires showed that fatigue symptom scores improved significantly (p < 0.001) after normalization of vitamin D levels. These findings suggest vitamin D supplementation could significantly improve the severity of fatigue symptoms.

Vitamin D is naturally produced in the body through exposure to sunlight and provides comprehensive health benefits. That includes strengthening bones, boosting immunity, building muscle strength and more.

470% more potent than regular vitamin D3 supplements, Liposomal Vitamin D3 protects the vitamin D from harsh gastric acid and delivers it directly to the cells with no side effects. With 240 softgels per box, it is the most cost effective vitamin D supplement in the market.

With regular vitamin D, the body does not absorb the full dosage due to breakdown before absorption. To compensate this loss, some may increase the dosage. However, excessive vitamin D intake can result in digestive discomforts like gas, bloating, diarrhoea, constipation, upset stomach and other intestinal issues.

Fat-soluble vitamin D3 are encapsulated in liposomes which are then transported to parts in the body where they are absorbed most effectively. These liposomes protect the vitamin D3 against oxidation and degradation as it moves through the body, even the harsh conditions of the gastrointestinal tract.

With improved absorbability bring greater health boosting benefits. Liposomal Vitamin D3 is better absorbed into the body than tablet, capsule or gummy forms.

1. Protects
Liposomes protect the nutrients from being broken down by digestive juice, allowing the nutrients to reach the intestines intact and absorbed into the bloodstream.

2. Encapsulates
Liposomes have a spherical-shaped hollow structure which encapsulates the vitamin D nutrient.

3. Delivers
Due to its similar structure to the cell membrane, the liposome fuses with the cell membrane, releasing the
encapsulated vitamin D into the cell.
 

Liposomal Vitamin D3 is made from lichen and is one of the first completely vegan source of natural vitamin D3 available on the market. Lichen can easily grow in large quantities, and is more sustainable as well.


Most vitamin D3 from animal sources comes from lanolin, an oil secretion found on sheep's wool. However, there is a potential risk of contamination from sheep dip or pesticides.

More benefits include
• Supports healthy inflammatory response
• Supports healthy blood glucose
• Supports healthy blood pressure
• Supports healthy heart health
• Boost energy levels
• Supports mental health

 

Prolonged insufficient oral intake and limited exposure to sunlight can cause a deficiency in vitamin D3. Some signs of deficiency are:
• Fatigue
• Bone pain
• Muscle aches, weakness, or cramps
• Mood changes, such as feelings of sadness
• Loss of appetite
• Hair loss
• Pale skin
• Poor immunity
• Poor sleep

Because Liposomal Vitamin D3 has liposomal protection, it safeguards the vitamin D from breakdown by gastric acid and allows for direct delivery into the body’s cells for utilization.


The integrity of the intestinal wall impacts the absorption of vitamin D. Higer levels of vitamin D levels are correlated with greater diversity and higher good bacteria count in the gut. Pair Liposomal Vitamin D3 with these high strength probiotics to boost intestinal health and vitamin D3 absorption.

veggie softgels
240 veggie softgels

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