Active ingredients per 2 capsules: 800 mg Agaricus blazei Murill (ABM) Extract + 300 mg Proprietary Blend Mushroom Extract (Agaricus blazei, Trametes versicolor, Ganoderma lucidum, Grifola frondosa, Lentinula edodes, Cordyceps sinensis and Cordyceps militaris)
2 veggie caps daily
Q. What is Bioactive Organic Agaricus Ultra?
A. Agaricus blazei Murrill (ABM) is a mushroom native to Brazil. For decades, its amazing healing properties had been traditionally tapped upon as a natural alternative remedy. Bioactive Organic Agaricus Ultra is formulated with 100% American grown Agaricus blazei Murill (ABM) extract and fortified with a proprietary blend of 7-Mushroom Extract (Agaricus blazei, Trametes versicolor, Ganoderma lucidum, Grifola frondosa, Lentinula edodes, Cordyceps sinensis and Cordyceps militaris). The bioactive compounds are extracted from the most potent parts of the 7 mushrooms – this includes the mycelium, fruit body, primordia, spores and extracellular compounds which were harvested through every stage of their life cycles. Bioactive Organic Agaricus Ultra provides ≥ 60% of total polysaccharides and ≥ 20% of 1-3, 1-6-beta-glucan. With the combined healing properties of multiple mushrooms, Bioactive Organic Agaricus Ultra is very potent in providing comprehensive immune protection, total health restoration and overall body wellness.
Q. What are the key criteria to consider when choosing a mushroom supplement?
A. Mushrooms comprise numerous forms of polysaccharides, including beta-glucans, which are beneficial to health. The total polysaccharides and 1-3, 1-6-beta glucan are quality markers of cordyceps or mushroom supplements; high amounts of these are favourable and indicative of the superior quality.
It is vital to note that another group of polysaccharides known as alpha-glucans (such as starch) provides no medicinal benefits. Mushroom typically contains <4% of alpha-glucans, thus, it is uncommon to find mushrooms supplements with a high number of alpha-glucans. However, an independent testing has found that some so-called “mushrooms” supplements contain over 70% starch and 0% beta glucans.
It is recommended to choose mushroom supplements with no added starch, mycelium or grains, which would otherwise inflate the total polysaccharides level but not the benefits. Beta-glucans are the secret behind the immune-modulating property of medicinal mushrooms. These potent compounds are known to increase the body’s resistance to viral and bacterial infection. Hence, always look for mushroom supplements with a high percentage of polysaccharides and beta-glucans on the label and not just polysaccharides. Bioactive Organic Agaricus Ultra is made from genuine mushroom extracts with no added starch, mycelium, grains, additive and fillers. It provides ≥ 60% of total polysaccharides and ≥ 20% of 1-3, 1-6-beta-glucans, over and above other unprecedented superiorities. It is your first choice for mushroom supplement.
Q. Is Bioactive Organic Agaricus Ultra safe for long-term consumption?
A. Bioactive Organic Agaricus Ultra is highly safe for long-term consumption. It is developed under stringent safety standards and the mushrooms used are not irradiated at any stage of the production. Instead, a proprietary technology is employed to destroy microorganisms to achieve microbial cleanliness for the extracts. In addition, the mushrooms are also non-GMO, USDA-certified organic, DNA-certified authentic, third-party tested and produced in FDA-certified Good Manufacturing Practice (cGMP) facility.
Q. What are the health benefits of Bioactive Organic Agaricus Ultra?
A. Each type of mushroom provides its unique polysaccharides that extend different health-enhancing effects to the body. Bioactive Organic Agaricus Ultra’s 7 + 1 harnesses all the healing properties of multiple mushrooms in one formula, to deliver a comprehensive range of defence mechanisms. It supports strong immune system and healthy inflammatory response to protect against infection and allergic responses. In addition, it also supports natural recovery and health restoration during remission care. Beyond these health benefits, this proprietary formula also supports cardiovascular (including blood glucose & blood lipids), liver and digestive health, reduces oxidative stress, supports healthy ageing, promotes youthful and healthy skin complexion and supports natural skin healing. Bioactive Organic Agaricus Ultra is highly recommended to be included into daily routine for strong immunity, speedy recovery and overall wellness.
Q. Does Bioactive Organic Agaricus Ultra cause "heatiness”?
A. No, it does not. Agaricus mushroom is a gentle tonic which no known side effects. It can be taken on a regular basis to maintain optimal immunity and wellness.
Q. When is the best time to take Bioactive Organic Agaricus Ultra?
A. Bioactive Organic Agaricus Ultra can be taken any time throughout the day, with or without food. If you are on medications, please keep at least 2-hour gap between Bioactive Organic Agaricus Ultra and medicines to ensure its efficacy is not compromised.
Q. Is Bioactive Organic Agaricus Ultra suitable for children?
A. Yes, children from age two can take Bioactive Organic Agaricus Ultra. In general, 1 capsule a day is sufficient for a child. For children who cannot swallow the capsule, capsules may be opened and mixed into a drink or food for ease of consumption.
Q. I always fall sick and take a long time to recover. Can Bioactive Organic Agaricus Ultra help improve my condition?
A. Indeed, it can. A weak immune system is the primary cause of many ailments and slow recovery. Bioactive Organic Agaricus Ultra is formulated with Agaricus blazei Murill extract, and fortified with power-packed 7-mushroom extract. This formula combines the synergistic benefits of 7 mushrooms to strengthen the immune system, this minimises the frequency of being ill and expedite recovery from an illness.
Q. Does Bioactive Organic Agaricus Ultra require a prescription?
A. No, Bioactive Organic Agaricus Ultra is a natural supplement and not a medicine. No prescription is required. Nonetheless, always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition before consuming any supplements.
Q. Is Bioactive Organic Agaricus Ultra safe for use during pregnancy and nursing?
A. Bioactive Organic Agaricus Ultra has not been studied for use during pregnancy and nursing. If you are pregnant or nursing, we strongly advise you to consult your physician before taking any supplements.
Research Proven Health Benefits of Agaricus blazei Murill (ABM) Extract
The following were extracted from clinical studies and for referencing purpose only. This does not imply that the product is claimed to treat, cure or prevent any disease.
1. Protect against infection
Agaricus blazei Murill (ABM) is a biologically active medicinal mushroom that has been used in traditional medicine and as a health food for prevention against infection and a range of diseases. ABM is rich in immunomodulating polysaccharides and beta-glucans, it helps to stimulate the immune cells, strengthen the immune system to help ward off pathogens.
In this animal test, Agaricus blazei Murill (ABM) extract or control was orally administered to some mice prior to infecting them with moderately virulent Streptococcus pneumoniae. Results showed that ABM extract protected the mice against S. pneumoniae, as shown by reduced bacteria in their blood as well as increased survival rate of the mice. This immune protection was suggested to be due to the involvement of ABM in native immune system. These findings suggest that ABM extract may be useful as a natural remedy to protect against bacterial and possibly other infections in humans.
Western equine encephalitis (WEE) is one of many mosquito-transmitted viral infections that can cause cytopathic effects, which is structural changes to host cells, leading to cell death. Some infected people, especially infants and elderly persons may develop brain inflammation. Among this, around 5 – 15% of brain inflammation cases are fatal, and about 50% of surviving infants would have permanent brain damage. There is no treatment for WEE other than supportive care.
In this in vitro study, the antiviral activities of Agaricus blazei Murill (ABM) extract on cells were investigated. The cells were cultured for 2 weeks after virus inoculation. ABM extract strongly suppressed the cytopathic effects induced by WEE virus, implying the beneficial effect of ABM extract on this viral infection.
2. Protect against allergy
Agaricus blazei have been shown to protect against allergy and asthma in animal models by modulating the T helper cell 1 (Th1) – T helper cell 2 (Th2) balance in the immune system. This medicinal mushroom upregulating Th1 response and downregulating Th2 response. During allergic reaction, the immune system overacts to an allergen by producing antibodies known as Immunoglobulin E (IgE), which is induced by a Th2 response, leading to symptoms in the nose, lungs, throat or on the skin.
In this animal test, mice were orally administered a mushroom extract, which consists mainly (82%) Agaricus blazei Murill (ABM) or control a day before or 19 days after the mice were induced allergen by being injected subcutaneously with model allergen ovalbumin (OVA). On day 26, their anti-OVA IgE (Th2 response) and IgG2a (Th1 response) antibodies were examined in the blood serum. Results showed that the mushroom extract given either before or after OVA immunization reduced the levels of anti-OVA IgE, but not IgG2a in the mice. This suggests that ABM extract may protect against allergy development and could potentially be used as a natural therapeutical substance against established allergy.
3. Provide antioxidant protection
Many mushrooms, including Agaricus blazei Murill (ABM) have been reported to provide antioxidant protection, which enables them to neutralise free radicals. The generation of free radicals can damage the cells, which appear to be a major contributor to ageing and degenerative diseases. Mushroom antioxidant components are found in the fruit bodies and mycelium, these include polysaccharides, phenolics, carotenoids and others.
In this in vitro study, the antioxidant properties of Agaricus blazei Murill (ABM) extract were evaluated. ABM extract provides antioxidant protection via three mechanisms. First, it inhibited enzymatic oxidative process, with 100% inhibition of horseradish peroxidase (HRP) and myeloperoxidase (MPO). Second, it inhibited cellular oxidative stress, with 80% inhibition of the oxidative burst of a type of white blood cells, known as polymorphonuclear neutrophils (PMNs). Third, it had direction action over reactive species, with 62% and 87% suppression of HOCl and superoxide anion radical, respectively. These findings suggest that ABM extract possesses significant antioxidant activity, indicating its potential application for nutraceutical and medicinal purposes.
5. Protect against paracetamol-induced brain and liver injury
Paracetamol is an over-the-counter medicine that is commonly used to relieve mild or moderate pain, such as headache, toothache or sprains and also reduce fever caused by colds and influenza. Overdose of paracetamol is toxic to the liver, it can lead to serious liver damage and possibly death. In addition to liver damage, paracetamol overdose is also toxic to the brain. It can induce morphological aberrations, implying the possibilities of higher brain impairments.
In this animal test, one group of mice was orally administered a single dose of paracetamol at 2 g/kg body weight, while another group was treated with the Agaricus blazei Murill (ABM) extract at 200 mg/kg body weight daily, for 21 days and paracetamol was given as a single dose of 2 g/kg body weight.
Results showed that the ABM pretreatment largely prevented the increase in the levels of liver enzymes in the blood plasma: aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH). Elevated AST, ALT, ALP and LDH could indicate liver damage or liver problems. ABM also normalised the TBARS levels in both the liver and brain tissues. TBARS (thiobarbituric acid reactive substances) are formed as a byproduct of lipid peroxidation and it is a widely used marker of oxidative stress. These findings indicate that ABM extract is able to provide a reasonable degree of protection against paracetamol-induced liver and brain injury.
6. Complement treatment therapy for chronic diseases
In this clinical trial, 100 patients with gynecologic diseaseswere treated either with carboplatin (300 mg/m2) plus VP16 (etoposide, 100 mg/m2) or with carboplatin (300 mg/m2) plus taxol (175 mg/m2) at 0, 3 and 6 weeks. ABM extract was orally administered every day. Compared to placebo group, ABM-treated group showed significantly higher natural killer (NK) cell activity. NK cells are immune cells which are capable of killing mutatedcells, detect and control early signs of diseases. In addition, ABM extract improved side effects of therapy, such as poor appetite, hair loss, emotional distress and general weakness. These findings suggest that ABM extract might be beneficial for patients with gynecologic disease who are undergoing treatment.
7. Normalise liver function in patients with chronic liver disease
In this 1-year open-label pilot study, patients with chronic liver disease for more than 3 years and not taking lamivudine, alpha-interferon or other drugs for chronic liver disease were orally administered 1500 mg Agarius blazei Murill (ABM) extract daily for 12 months. The level of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) was measured. High levels of AST and/or ALT may be a sign of liver damage or disease. At the end of the study, ABM extract was shown to result in a decrease of mean level of AST and ALT, indicating the potential benefit of ABM extract in normalising liver function of patients with chronic liver disease
8. Manage blood glucose levels
In this randomised, double-blind, placebo-controlled clinical trial, 72 type 2 diabetes patients with extremely high blood glucose levels who having been taking gliclazide and metformin for more than 6 months were orally administered either 1500 mg Agaricus blazei Murill (ABM) extract or placebo daily for 12 weeks. At the end of the study, patients received ABM extract showed significantly lower HOMA-IR index, which is an insulin resistance score. High HOMA-IR values indicate low insulin sensitivity (insulin resistance), while low HOMA-IR values indicate high insulin sensitivity.
Adiponectin is a protein hormone and adipokine that is involved in regulating glucose levels. In human, adiponectin levels in blood plasma are significantly lower in insulin-resistant states. In this study, oral administration of ABM extract for 12 weeks resulted in 20% increase in plasma adiponectin concentration, while those taking placebo showed 12% decrease. These findings suggest that ABM extract in combination with metformin and gliclazide reduces insulin resistance among subjects with high, unhealthy blood glucose levels.
Medicinal mushrooms are coveted for their healing properties. But each mushroom contains its unique polysaccharides that extend different health-enhancing effects to the body, so a single mushroom would not be efficient to cover all bases of immune defence.
Bioactive Organic Agaricus Ultra (ABM) is a proprietary formula made with 100% organic premium grade ABM extract plus an unrivalled 7-nutraceutical mushroom extract comprising Agaricus blazei Murill, Trametes versicolor, Ganoderma lucidum, Grifola frondosa, Lentinula edodes, Cordyceps sinensis and Cordyceps militaris. The combined spectrum of 1-3, 1-6 beta-glucan and polysaccharides from 7 different mushrooms provides a comprehensive range of defence mechanisms to build a solid foundation for strong immunity.
Agaricus blazei Murill (ABM) mushroom is native to Brazil, coveted for its medicinal properties. Researchers believe that the bioactive compounds in ABM are more potent than those in other mushrooms. It has been commonly used in traditional alternative remedies to manage atherosclerosis (build-up of fatty deposits in artery wall), liver inflammation, high blood lipids, skin inflammation and other chronic diseases.
Bioactive Organic Agaricus Ultra lets you reap the most of the active compounds from multiple mushrooms for a wide spectrum of health benefits in one supplement. This premium grade proprietary blend is developed via a multi-layered technology and enzymatic processing to derive high potency micromolecular compounds which are readily absorbed and utilised to provide best efficacy.
• Supports strong immune system
• Protects cells against destructive cells
• Protects against infection and allergic response
• Supports healthy inflammatory response
• Supports healthy blood glucose & blood lipids
• Promotes youthful and healthy complexion, supports natural skin healing
• Supports healthy ageing
• Supports cardiovascular health
• Supports liver and digestive health
• Helps protect brain and liver from damage by paracetamol overdose
• Supports natural recovery and restores health during remission care
Different mushrooms contain different types of polysaccharides with unique healing properties. The higher the polysaccharides content, the better the quality. Polysaccharides such as 1-3 and 1-6 beta-glucan are beneficial to health. However, others such as Alpha-Glucans do not have any medicinal benefits at all.
Many mushroom supplements in the market claim to offer a high polysaccharide percentage but fail to disclose the alpha-glucan and beta-glucan content. Ideally, a mushroom supplement should have low alpha-glucan and high beta-glucan percentage.
Contents: 90 veggie caps
|90 veggie caps|