Although not particularly tasty, whole grape seeds are completely edible, and scientific evidence suggests that they are good for you, too. Packed with essential fatty acids, amino acids and powerful antioxidant, OPCs, these little bitter seeds have been associated with a whole slew of health benefits such as improving cardiovascular health, reducing leg swelling and varicose veins, providing some protection against certain types of cancers, as well as offering weight loss benefits. Blending whole grapes into a juice with the seeds intact is one way to tap on the benefits of grape seeds.