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Research Proven Benefits of Femme Iron Complex
The following are extracted from published clinical studies, in-house studies, and/or case studies and are for reference purposes only. This does not imply that the product from Lifestream Group Pte Ltd is claimed to replicate the same results produced in the studies. This information is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions about a medical condition, please consult your physician or other qualified healthcare providers. Any statements or claims made have not been evaluated by the relevant regulatory bodies and are not intended to diagnose, treat, cure, or prevent any disease.
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Increase haemoglobin levels
In this double-blind study, 34 anemic school children were orally administered 10 mg ferrous sulfate per kilogram body weight daily for 3 months. Their blood profile and learning achievement data were collected before and after the treatment period. The results showed that iron supplementation resulted in remarkable improvement to the levels of haemoglobin (protein in red blood cells that carries oxygen), hemocrit (proportion of red blood cells in blood) and transferrin saturation. Transferrin is a type of protein that binds and transports iron throughout the body. Normal transferrin saturation is 15% to 50%, with transferrin saturation less than 15% indicates iron deficiency, while more than 50% suggests iron overload. In addition, iron supplementation increases the learning achievement scores of the school children. These findings suggest the beneficial effects of iron supplementation on hemoglobin levels and learning ability of school children.
Improve endurance
In this double-blind study, 42 iron-depleted, nonanemic women aged 18 to 33 years old were orally administered 100 mg ferrous sulfate or placebo daily for 6 weeks. For the final 4 weeks of the study, subjects were trained for 30 minutes daily and 5 days per week at 75-85% of the maximum heart rate.
Compared to placebo group, iron supplementation increased serum ferritin levels. Ferritin is a blood protein that contains iron and ferritin test reveals the amounts of iron stores in the body. In addition, iron supplementation resulted in significant decrease in 15-km cycle ergometer time trial after 4 weeks of exercise training, which could be partially attributed to increase in serum ferritin and haemoglobin levels. These results suggest iron supplementation improves physical performance and endurance in iron-depleted women.
Fight fatigue
In this study, 198 nonanemic iron-deficient women (aged 18 – 53 years) with unexplained fatigue with low ferritin were orally administered ferrous sulfate (80 mg of elemental iron daily) or placebo for 12 weeks. Their fatigue condition was assessed using the Current ad Past Psychological Scale and biological markers were measured at 6 and 12 weeks. Compared to placebo, iron supplementation significantly decreased the mean score on the Current and Past Psychological Scale for fatigue, and increased hemoglobin and ferritin levels. These findings suggest the beneficial effects of iron supplementation in relieving fatigue in nonanemic iron-deficient women.
Improve cognitive function
In this study, adolescent girls with non-anaemic iron deficiency were orally administered iron supplementation, which is 650 mg ferrous sulfate twice daily or placebo for 8 weeks. The effects of iron supplementation were assessed by questionnaires, haematological and cognitive test before and after supplementation. Iron supplementation significantly improved the iron status, as well as verbal learning and memory, which were assessed using The Hopkins Verbal Learning Test (HVLT). These findings suggest the beneficial effects of iron supplementation on adolescent girls.
Improve work performance
In this study, 80 iron-deficient, nonpregnant women were orally administered ferrous sulfate (60 or 120 mg Fe per day) or placebo for 12 weeks. Their energy expenditure was estimated during 3 days by heart rate (HR) recording, while production efficiency (PE) was calculated as the ratio of productivity to energy expenditure.
Iron supplementation significantly increased hemoglobin and serum ferritin levels. In addition, the heart rate at work decreased significantly in iron-treated group, which implies a higher degree of physical fitness and energy expenditure. Furthermore, production efficiency and productivity increased significantly in the iron-treated group. These findings suggest that iron supplementation improved work performance by allowing the same amount of work to be done at a lower energy cost.
Improve mood
In this study, 70 non-anemc women with postpartum depression (PPD) were orally administered 50 mg elemental iron daily or placebo for 6 weeks, started from one week after delivery, and their improvement of PPD symptoms were compared. Compared to placebo group, ferritin was significantly higher and rate of iron deficiency was significantly lower in the iron-treated group. The Edinburgh Postnatal Depression Scale (EPDS) was used to identify possible postpartum depression. The EPDS score was significantly decreased in the iron-treated group (p < 0.001), but not in the placebo group (p = 0.13). The improvement rate for PPD was significantly higher in the iron-treated group than placebo. These findings suggest that early iron supplementation in women with PPD significantly improves iron stores and depression symptoms.
Poor Complexion
-Fatigue
-Pale skin
Low Energy & Productivity
-Shortness of breath
-Fast heartbeat
-Headaches or dizziness
Just not Yourself
-Hair loss
-Brittle nails
-Cold hands & feet
-Craving for ice
Upset Stomach
The most common complain about oral intake of an iron supplement is gastrointestinal discomforts, such as constipation, stomach cramps, nausea, diarrhoea and darkening of stools.
Low Iron Absorption
Research indicates that the absorption of iron from supplements can be limited, particularly when they contain calcium or magnesium. (Clin. Ther. 10: 429 – 435 (1988)).
Unpleasant Metallic Taste
After taking iron supplements, the metallic taste may persist in the mouth for an extended period of time.
SunActive® Fe-230 is a microsomal iron fortifier that is colourless, odourless and tasteless. Without metallic iron taste, this microencapsulated ferric pyrophosphate has superior absorption and bioavailability, which effectively helps replenish iron stores in the body.
Ferric pyrophosphate is a poorly water-soluble iron compound, resulting in suboptimal absorption and low efficacy. However, this changes when used with the SunActive® endosomal Nutrient Delivery System (NDS). This patented technology incorporates micronization and microencapsulation of the iron compound, enabling it to disperse readily in water, thus improving its absorption and bioavailability.
SunActive® transforms iron particles into micronized salt particles, which are then encapsulated in an emulsifier layer with a particle size of 0.3 μm. This process results in a stable dispersion with enhanced bioavailability.
SunActive® iron particles are absorbed like liposomes by M cells, a unique type of intestinal epithelial cell, via endocytosis. This bypasses the need to compete with other mineral ions for binding to the DMT1 transporter.
SunActive® Endosomal Fe is a unique type of iron that gets absorbed by your body through a process called endocytosis. In this process, the cell membrane surrounds the iron particles and forms a small pouch, or vesicle, that carries them into the cell. This unique way of absorption gives SunActive® a significant advantage over typical iron particles.
Most iron particles get absorbed through a method involving Divalent Metal Transporter 1 (DMT1). This transporter helps move iron into the cells lining your intestines. But when iron gets absorbed this way, it has to compete with other ions like calcium, zinc, and copper. This competition can slow down and interrupt the absorption of iron.
However, SunActive® Endosomal Fe doesn't have to compete in this way. By being absorbed through endocytosis, it ensures a steady and optimal intake of iron into your body.
What's more, SunActive® Endosomal NDS has the added benefit of not having a metallic taste and not reacting as much with other substances. SunActive® Endosomal iron also doesn't contain any added flavors, colors, or preservatives. Plus, it remains stable when exposed to heat, salt, changes in pH, and oxidation.
Most minerals are absorbed in the small intestines through channels that transport ions, which can make it hard for different minerals to be absorbed at the same time. However, SunActive® Fe-P230 is unique because it has a special coating that allows the iron particles to be absorbed in a different way through specialized cells in the intestines called M cells.
Choose the right form - Regular iron supplements can cause discomfort in the stomach and gut, leading to issues like constipation, pain, and nausea. However, SunActive® Fe-P230 is a gentler alternative that is formulated with ferric pyrophosphate. This makes it suitable for people who have trouble with regular iron supplements.
Additionally, ferric pyrophosphate is a highly bioavailable form of iron, with an absorption rate of 83-94%. This means that SunActive® Fe-P230 is an effective solution for replenishing iron levels in the body.
Beetroot fibers aids in the intestinal absorption of iron, thereby improving iron-deficiency anemia. In addition, fiber helps promote the feelings of fullness and decrease appetite, thereby supporting healthy weight management by reducing calorie intake.
Although beetroots can be grown in other prefectures in Northern Japan, beetroots grown in Hokkaido are generally ranked the best.
Numerous studies have demonstrated that vitamin C can enhance the absorption of iron in a dose- dependent manner.
1. reducing ferric (Fe3+) to ferrous iron (Fe2+), which is a more bioavailable form of iron
2. counteract substances like phytate, polyphenols, calcium, and milk proteins, which can block iron absorption.
Vitamin B2 is important for energy production, breakdown of fats, steroid hormones, and medication, as well as conversion of vitamin B6 into coenzyme.
Vitamin B6 contribute to immune function and hemoglobin formation, as well as neuro health.
Vitamins B9 and B12 collaborate to form new red blood cells. Vitamin B9 is especially important during infancy, adolescence and pregnancy, which the growth of cells and tissues take place rapidly
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